Drug Profile

SIM 0505

Alternative Names: SIM-0505

Latest Information Update: 19 Jun 2025

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At a glance

Originator Simcere Zaiming
Class Antineoplastics
Mechanism of Action DNA topoisomerase I inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Highest Development Phases

Phase I Solid tumours

Most Recent Events

16 Jun 2025 SIM 0505 licensed to NextCure worldwide excluding china
16 Jun 2025 NextCure plans a clinical trial in the US in third quarter of 2025
26 Feb 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater) in China (Parenteral) (NCT06792552)

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