Drug Profile

OpSCF

Alternative Names: INS-1148

Latest Information Update: 23 Dec 2025

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At a glance

Originator Opsidio
Class Anti-inflammatories; Antifibrotics; Monoclonal antibodies; Skin disorder therapies
Mechanism of Action Stem cell factor inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Atopic dermatitis
No development reported Fibrosis; Inflammation

Most Recent Events

17 Dec 2025 Insmed acquires OpSCF from Opsido
17 Dec 2025 Insmed plans phase II trial for Interstitial lung disease and Asthma
28 Jun 2025 No recent reports of development identified for preclinical development in Fibrosis in USA (SC)

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