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INS 1148

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Drug Profile

INS 1148

Alternative Names: INS-1148; OpSCF

Latest Information Update: 13 Mar 2026

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At a glance

  • Originator Opsidio
  • Developer Insmed; Opsidio
  • Class Anti-inflammatories; Antifibrotics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Stem cell factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Asthma; Interstitial lung diseases
  • Discontinued Atopic dermatitis; Fibrosis; Inflammation

Most Recent Events

  • 23 Feb 2026 Insmed has patent protection for INS 1148 in USA, Europe and Japan
  • 23 Feb 2026 Phase-I clinical trials in Asthma in USA (unspecified route)
  • 23 Feb 2026 Phase-I clinical trials in Interstitial lung diseases in USA (unspecified route)

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