Drug Profile

PF 07899895

Alternative Names: PF-07899895

Latest Information Update: 07 Apr 2026

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At a glance

Originator Pfizer
Class 2 ring heterocyclic compounds; Amines; Cyclohexanes; Imidazoles; Methyl ethers; Nitriles; Phenyl ethers; Pyridines; Small molecules; Sulfides
Mechanism of Action Salt-inducible kinase-2 inhibitors; SIK1 protein inhibitors; SIK3 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

06 Apr 2026 Chemical structure information added.
03 Feb 2026 Discontinued - Phase-I for Ulcerative colitis (In volunteers) in Belgium (PO, Controlled release)
03 Feb 2026 Discontinued - Phase-I for Ulcerative colitis (In volunteers) in Belgium (PO, Immediate release)

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