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MTX 463

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Drug Profile

MTX 463

Alternative Names: MTX-463

Latest Information Update: 08 Aug 2024

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At a glance

  • Originator Mediar Therapeutics
  • Class Antifibrotics; Monoclonal antibodies
  • Mechanism of Action WISP1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Idiopathic pulmonary fibrosis

Most Recent Events

  • 07 Aug 2024 MTX 463 receives Fast Track designation for Idiopathic pulmonary fibrosis [Parenteral] (In volunteers) in USA
  • 07 Aug 2024 MTX 463 receives Orphan Drug status for Idiopathic pulmonary fibrosis in USA
  • 17 May 2024 Pharmacodynamics and adverse events data from a preclinical trial in Fibrosis presented at the 120th International Conference of the American Thoracic Society (ATS-2024)

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