Drug Profile

INCB 160058

Alternative Names: INCB-100658; INCB-160058; JAK2V617Fi

Latest Information Update: 27 Aug 2026

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At a glance

Originator Incyte Corporation
Class Antineoplastics; Small molecules
Mechanism of Action Janus kinase 2 inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Myeloproliferative disorders

Most Recent Events

28 Jul 2026 Discontinued - Phase-I for Myeloproliferative disorders (In volunteers) in Australia (PO)
28 Jul 2026 Discontinued - Phase-I for Myeloproliferative disorders in Norway, Switzerland, United Kingdom, USA, Germany, Germany, Italy, France, France, Canada (PO)
31 Mar 2026 Incyte Corporation initiates enrolment in a phase-I trial for Myeloproliferative disorders (PO)

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