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INCB 160058

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Drug Profile

INCB 160058

Alternative Names: INCB-100658; INCB-160058; JAK2V617Fi

Latest Information Update: 03 Mar 2026

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At a glance

  • Originator Incyte Corporation
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Janus kinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Myeloproliferative disorders

Most Recent Events

  • 06 Dec 2025 Pharmacodynamics data from preclinical trials in Myeloproliferative disorders presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)
  • 19 Aug 2025 Incyte Corporation completes phase-I trial in Myeloproliferative disorders (In volunteers) in Australia (PO, Tablet) (NCT06213818)
  • 08 Aug 2024 Phase-I clinical trials in Myeloproliferative disorders in USA, United Kingdom, Switzerland, Italy, Norway, Germany, France, Canada (PO) (NCT06313593)

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