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REM 422

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Drug Profile

REM 422

Alternative Names: REM-422

Latest Information Update: 17 Sep 2024

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At a glance

  • Originator Remix Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto-oncogene protein c-myb expression inhibitors; RNA degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Adenoid cystic carcinoma; Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Adenoid cystic carcinoma; Myelodysplastic syndromes

Most Recent Events

  • 13 Jun 2024 Pharmacodynamics data from a preclinical studies in Acute myeloid leukemia presented at the 29th Congress of the European Haematology Association (EHA-2024)
  • 13 Jun 2024 Pharmacodynamics data from preclinical trials in Acute myeloid leukaemia released by Remix Therapeutics
  • 02 May 2024 REM 422 receives Orphan Drug status for Acute myeloid leukaemia in USA

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