Drug Profile

AZD 4144

Alternative Names: AZD-4144

Latest Information Update: 15 Dec 2025

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At a glance

Originator AstraZeneca
Class Anti-inflammatories; Cardiovascular therapies; Small molecules; Urologics
Mechanism of Action NLRP3 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

15 Dec 2025 Phase-I clinical trials in Cardiovascular disorders in Hungary, Romania, Bulgaria, USA (PO) (NCT06675175)
09 Dec 2025 Phase-I clinical trials in Renal failure in Hungary, Romania, Bulgaria (PO) (NCT06675175)
09 Dec 2025 AstraZeneca completes a phase I trial in Cardiovascular disorders and Renal failure in USA, Bulgaria, Hungary and Romania (NCT06675175)

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