Drug Profile

AZD 4144

Alternative Names: [14C] AZD 4144; AZD-4144

Latest Information Update: 15 Apr 2026

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At a glance

Originator AstraZeneca
Class Anti-inflammatories; Cardiovascular therapies; Small molecules; Urologics
Mechanism of Action NLRP3 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

11 Feb 2026 Phase-I clinical trials in Kidney disorders (In volunteers) in United Kingdom (IV) (NCT07518459)
11 Feb 2026 Phase-I clinical trials in Kidney disorders (In volunteers) in United Kingdom (PO) (NCT07518459)
15 Dec 2025 Phase-I clinical trials in Cardiovascular disorders in Hungary, Romania, Bulgaria, USA (PO) (NCT06675175)

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