Drug Profile

AZD 4144

Alternative Names: AZD-4144

Latest Information Update: 03 Jul 2025

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At a glance

Originator AstraZeneca
Class Anti-inflammatories; Cardiovascular therapies; Small molecules; Urologics
Mechanism of Action NLRP3 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

12 Jun 2025 AstraZeneca completes a phase I pharmacokinetic trial (In volunteers) in United Kingdom (PO) (NCT06925854)
28 Apr 2025 AstraZeneca plans a phase I pharmacokinetics trial in healthy volunteers (In volunteers) in United Kingdom (PO) in April 2025 (NCT06948006)
23 Apr 2025 AstraZeneca initiates a phase I pharmacokinetics trial (In volunteers) in United Kingdom (PO)(NCT06948006)

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