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MB 105

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Drug Profile

MB 105

Alternative Names: MB-105 - March Biosciences; MB105

Latest Information Update: 16 Aug 2024

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At a glance

  • Originator March Biosciences
  • Developer Baylor College of Medicine; March Biosciences
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Precursor T-cell lymphoblastic leukaemia-lymphoma; T-cell lymphoma
  • Preclinical Chronic lymphocytic leukaemia; Mantle-cell lymphoma

Most Recent Events

  • 02 Aug 2024 March Biosciences plans a phase II trial for T-cell Lymphoma (Second-line therapy or greater) in February 2025 (NCT06534060)
  • 09 Nov 2023 Phase-I clinical trials in Precursor T-cell lymphoblastic leukaemia-lymphoma (Second-line therapy or greater) in USA (Parenteral) (NCT03081910)
  • 09 Nov 2023 Phase-I clinical trials in T-cell lymphoma (Second-line therapy or greater) in USA (Parenteral) (NCT03081910)

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