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AMG 355

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Drug Profile

AMG 355

Alternative Names: AMG-355

Latest Information Update: 28 Aug 2026

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At a glance

  • Originator Amgen
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CCR8 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 04 Aug 2026 Discontinued - Phase-I for Solid tumours (Late-stage disease) (IV)
  • 04 Aug 2026 Discontinued - Phase-I for Solid tumours (Metastatic disease, Combination therapy, Late-stage disease) in Canada, Japan, Taiwan, Netherlands, Poland, USA, Australia, France, Switzerland, Spain (IV) (Amgen pipeline, August 2026)
  • 04 Aug 2026 Discontinued - Phase-I for Solid tumours (Metastatic disease, Late-stage disease, Monotherapy) in Australia, France, Netherlands, South Korea, Taiwan, USA, Switzerland, Spain, Poland, Japan, Canada (IV) (Amgen pipeline, August 2026)

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