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K 8

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Drug Profile

K 8

Alternative Names: Inflammasome inhibitor-Inflammasome Therapeutics; K-8; Kamuvudine-8; SOM-401

Latest Information Update: 01 Dec 2025

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At a glance

  • Originator Inflammasome Therapeutics
  • Class Eye disorder therapies
  • Mechanism of Action NLRC4 protein inhibitors; NLRP3 protein inhibitors; Nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Diabetic macular oedema; Dry macular degeneration

Most Recent Events

  • 25 Nov 2025 University of Kentucky and Inflammasome Therapeutics complete enrolment in a phase I trial in Dry macular degeneration in USA (Intravitreous) (NCT06164587)
  • 20 Jun 2024 Inflammasome Therapeutics completes a phase-I trial in Diabetic macular oedema in USA (Intravitreous), (NCT05699759),
  • 05 Mar 2024 Phase-I clinical trials in Dry macular degeneration in USA (Intravitreous) (NCT06164587)

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