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K 8

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Drug Profile

K 8

Alternative Names: Inflammasome inhibitor-Inflammasome Therapeutics; K-8; Kamuvudine-8; SOM-401

Latest Information Update: 22 Jul 2026

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At a glance

  • Originator Inflammasome Therapeutics
  • Class Eye disorder therapies
  • Mechanism of Action NLRC4 protein inhibitors; NLRP3 protein inhibitors; Nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Dry macular degeneration
  • No development reported Diabetic macular oedema

Most Recent Events

  • 17 Jul 2026 Updated efficacy and adverse events data from a phase I/II trial in Dry macular degeneration released by Inflammasome Therapeutics
  • 17 Jul 2026 Inflammasome Therapeutics plans a global phase III pivotal trial in Dry macular degeneration (Intravitreous, Controlled-release, Implant)
  • 15 May 2026 University of Kentucky completes a phase I/II trial in Dry macular degeneration in USA (Intravitreous) (NCT06164587)

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