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NMRA 266

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Drug Profile

NMRA 266

Alternative Names: NMRA-266

Latest Information Update: 19 Apr 2024

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At a glance

  • Originator Vanderbilt University
  • Developer Neumora Therapeutics; Vanderbilt University
  • Class Antipsychotics; Behavioural disorder therapies; Small molecules
  • Mechanism of Action Muscarinic M4 receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Schizophrenia
  • Preclinical Psychiatric disorders

Most Recent Events

  • 15 Apr 2024 US FDA places clinical hold on phase-I trial of NMRA 266 for Schizophrenia (In volunteers) in USA
  • 27 Nov 2023 Neumora Therapeutics has patent protection for NMRA 266 from Vanderbilt University, including composition of matter patent extending to 2042
  • 27 Nov 2023 Phase-I clinical trials in Schizophrenia (In volunteers) in USA (PO)

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