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RPT 1G

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Drug Profile

RPT 1G

Alternative Names: RPT-1G

Latest Information Update: 07 Mar 2026

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At a glance

  • Originator Remedy Plan Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Nicotinamide phosphoribosyltransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Haematological malignancies; Myelodysplastic syndromes
  • Preclinical Solid tumours

Most Recent Events

  • 06 Dec 2025 Pharmacodynamics data from the preclinical trial in Non-Hodgkin's lymphoma presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)
  • 06 Dec 2025 Adverse events, pharmacodynamics and pharmacokinetics data from the phase I trial in Haematological malignancies presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)
  • 04 Dec 2025 Phase-I clinical trials in Acute myeloid leukaemia (Second-line therapy or greater) (PO) prior to December 2025 (NCT07107126)

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