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RPT 1G

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Drug Profile

RPT 1G

Alternative Names: RPT-1G

Latest Information Update: 08 Jul 2026

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At a glance

  • Originator Remedy Plan Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Nicotinamide phosphoribosyltransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Haematological malignancies; Myelodysplastic syndromes
  • Preclinical Solid tumours

Most Recent Events

  • 22 Apr 2026 Pharmacodynamics data from a preclinical study in Solid tumour presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR 2026)
  • 17 Apr 2026 Pharmacodynamics data from a preclinical study in Solid tumour presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR 2026) (ADNM)
  • 17 Apr 2026 Pharmacodynamics and adverse events data from phase I trial in Haematological malignancies presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR-2026)

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