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RPT 1G

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Drug Profile

RPT 1G

Alternative Names: RPT-1G

Latest Information Update: 15 Aug 2025

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At a glance

  • Originator Remedy Plan Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Nicotinamide phosphoribosyltransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Haematological malignancies
  • Preclinical Solid tumours

Most Recent Events

  • 06 Aug 2025 Remedy Plan Therapeutics plans a phase-I trial for Acute myeloid leukemia and Myelodysplastic syndrome (Second-line therapy or greater) in December 2025 (PO) (NCT07107126)
  • 13 May 2025 Remedy Plan Therapeutics plans a phase I/II trial for Acute myeloid leukemia and Myelodysplastic syndromes (Monotherapy, Combination-therapy) in second half of 2025 (PO, Capsule)
  • 10 Dec 2024 Pharmacodynamics data from preclinical trials in Haematological malignancies released byRemedy Plan Therapeutics ,

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