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BMS 986453

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Drug Profile

BMS 986453

Alternative Names: Anti BCMA and GPRC5D dual targeting CAR T cell therapy - Juno Therapeutics; BCMAxGPRC5D CAR-T therapy - Juno therapeutics; BMS-986453

Latest Information Update: 17 Jan 2024

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At a glance

  • Originator Juno Therapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Multiple myeloma

Most Recent Events

  • 09 Jan 2024 Phase-I clinical trials in Multiple myeloma (Second-line therapy or greater) in USA (Parenteral) (NCT06153251)
  • 05 Dec 2023 Preclinical trials in Multiple myeloma in USA (Parenteral)
  • 01 Dec 2023 Juno Therapeutics plans a phase I trial for Multiple myeloma (Second-line therapy or greater) (Parenteral) in January 2024 (NCT06153251)

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