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S 4321

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Drug Profile

S 4321

Alternative Names: PD-1-FcγRIIb; S-4321

Latest Information Update: 17 Apr 2025

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At a glance

  • Originator Seismic Bio
  • Class Bispecific antibodies
  • Mechanism of Action Fc gamma receptor IIB agonists; Programmed cell death 1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Autoimmune disorders

Most Recent Events

  • 03 Apr 2025 Phase-I clinical trials in Autoimmune disorders (In volunteers) in Australia (IV) (NCT06877611)
  • 03 Apr 2025 Phase-I clinical trials in Autoimmune disorders (In volunteers) in Australia (SC) (NCT06877611)
  • 18 Nov 2024 Seismic Therapeutic plans a phase-I trial (In volunteers) for Autoimmune disorders in March 2025 (SC) (NCT06877611)

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