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S 1117

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Drug Profile

S 1117

Alternative Names: Pan-IgG protease-Seismic Therapeutics; S-1117

Latest Information Update: 23 Apr 2026

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At a glance

  • Originator Seismic Bio
  • Class Enzymes; Immunoglobulin Fc fragments; Recombinant fusion proteins; Recombinant proteins
  • Mechanism of Action Immunoglobulin G degraders; Immunosuppressants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Autoimmune disorders
  • Preclinical Idiopathic thrombocytopenic purpura

Most Recent Events

  • 24 Oct 2025 Pharmacodynamics data from a preclinical studies in autoimmune disorders presented at the ACR Convergence 2025 (ACR/ARP-2025)
  • 09 Mar 2025 Phase-I clinical trials in Autoimmune disorders (In volunteers) in Australia (IV) (NCT06828393)
  • 09 Mar 2025 Phase-I clinical trials in Autoimmune disorders (In volunteers) in Australia (SC) (NCT06828393)

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