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KRRO 110

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Drug Profile

KRRO 110

Alternative Names: KRRO-110

Latest Information Update: 14 May 2025

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At a glance

  • Originator Korro Bio
  • Class Oligonucleotides
  • Mechanism of Action Alpha 1-antitrypsin modulators; RNA modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Alpha 1-antitrypsin deficiency
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Alpha 1-antitrypsin deficiency

Most Recent Events

  • 07 May 2025 Korro Bio receives approval from the regulatory body for the first-in human phase I/IIa REWRITE trial in New Zealand
  • 18 Mar 2025 Adverse events data from the phase I/IIa REWRITE trial in Alpha-1 antitrypsin deficiency released by Korro Bio
  • 14 Mar 2025 KRRO 110 receives Orphan Drug status for Alpha 1-antitrypsin deficiency in USA

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