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GLB 002

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Drug Profile

GLB 002

Alternative Names: GLB-002

Latest Information Update: 27 Feb 2026

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At a glance

  • Originator GluBio Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action IKZF1 protein modulators; IKZF3 protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Non-Hodgkin's lymphoma
  • Preclinical Diffuse large B cell lymphoma; Multiple myeloma

Most Recent Events

  • 06 Dec 2025 Efficacy, adverse event, pharmacokinetics and pharmacodynamics data from phase-I clinical trials in Non-Hodgkin's lymphoma presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)
  • 11 Jan 2024 Phase-I clinical trials in Non-Hodgkin's lymphoma (Second-line therapy or greater) in China (PO) (NCT06219356)
  • 15 Dec 2023 Preclinical trials in Diffuse large B cell lymphoma in USA (unspecified route), prior to December 2023 (GluBio Therapeutics pipeline, December 2023)

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