Drug Profile

MZE 782

Alternative Names: MZE-782

Latest Information Update: 16 Sep 2025

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At a glance

Originator Maze Therapeutics
Class Small molecules; Urologics
Mechanism of Action SLC6A19 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Phenylketonuria; Renal failure

Most Recent Events

11 Sep 2025 Pharmacokinetics, adverse events and pharmacodynamics data from a phase I trial in Renal failure released by Maze Therapeutics
12 Aug 2025 Maze Therapeutics plans a two separate phase II trial for Chronic kidney disease and Phenylketonuria in December 2026
10 Aug 2025 Maze Therapeutics withdraws a phase I trial in Renal failure (In volunteers) in Australia(PO), prior to enrollment (ACTRN12625000488404)

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