Drug Profile

MZE 782

Alternative Names: MZE-782

Latest Information Update: 19 Aug 2026

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At a glance

Originator Maze Therapeutics
Class Small molecules; Urologics
Mechanism of Action SLC6A19 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Phenylketonuria
Phase I Renal failure

Most Recent Events

12 Aug 2026 Maze Therapeutics plans to initiate a phase II trial for Chronic kidney disease in first half of 2027
23 Jun 2026 Phase-II clinical trials in Phenylketonuria in USA (PO) (NCT07694440)
25 Mar 2026 Maze Therapeutics plans to initiate a phase II trial for Phenylketonuria in mid of 2026.

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