Drug Profile

MZE 782

Alternative Names: MZE-782

Latest Information Update: 07 Apr 2026

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At a glance

Originator Maze Therapeutics
Class Small molecules; Urologics
Mechanism of Action SLC6A19 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Phenylketonuria; Renal failure

Most Recent Events

25 Mar 2026 Maze Therapeutics plans to initiate a phase II trial for Chronic kidney disease in second half of 2026.
25 Mar 2026 Maze Therapeutics plans to initiate a phase II trial for Phenylketonuria in mid of 2026.
11 Sep 2025 Pharmacokinetics, adverse events and pharmacodynamics data from a phase I trial in Renal failure released by Maze Therapeutics

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