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TRX 214

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Drug Profile

TRX 214

Alternative Names: TRX-214; TRX-214-1002

Latest Information Update: 17 Jun 2025

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At a glance

  • Originator Therapex
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action Peptide-chain-release factor 3 degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia

Most Recent Events

  • 25 Apr 2025 Preclinical trials in Acute myeloid leukaemia in South Korea (unspecified route) prior to April 2025
  • 25 Apr 2025 Pharmacodynamics and pharmacokinetics data from a preclinical study in Acute myeloid leukaemia presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 18 Dec 2023 Early research in Cancer in South Korea (unspecified route), prior to December 2023 (Therapex pipeline, December 2023)

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