Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

ORKA 001

Next Previous
Drug Profile

ORKA 001

Alternative Names: ORKA-001; ORKA-021; PR-035

Latest Information Update: 11 Mar 2026

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Paragon Therapeutics
  • Developer Oruka Therapeutics; Paragon Therapeutics
  • Class Antibodies; Antipsoriatics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Interleukin-23 subunit p19 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Plaque psoriasis

Most Recent Events

  • 23 Feb 2026 Oruka Therapeutics initiates a phase II open-label extension trial for Plaque psoriasis in USA, Canada (SC, Injection) (NCT07449702)
  • 03 Dec 2025 Oruka Therapeutics initiates enrolment in the phase IIb EVERLAST-B trial for Plaque psoriasis in USA (SC, Injection) (NCT07290569)
  • 17 Sep 2025 Oruka Therapeutics plans a phase IIb EVERLAST-B trial for Plaque psoriasis in first half of 2026

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top