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ORKA 002

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Drug Profile

ORKA 002

Alternative Names: ORKA 021; ORKA-002; PR-029

Latest Information Update: 02 Jun 2025

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At a glance

  • Originator Paragon Therapeutics
  • Developer Oruka Therapeutics; Paragon Therapeutics
  • Class Antibodies; Antipsoriatics; Antirheumatics; Monoclonal antibodies
  • Mechanism of Action Interleukin 17 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Psoriasis; Psoriatic arthritis

Most Recent Events

  • 20 May 2025 Oruka Therapeutics plans a phase II trial for Psoriasis in first half of 2026
  • 19 May 2025 Phase-I clinical trials in Psoriasis (In volunteers) in New Zealand (SC) (NCT06944379)
  • 19 May 2025 Phase-I clinical trials in Psoriatic arthritis (In volunteers) in New Zealand (SC) (NCT06944379)

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