QHL 108
Alternative Names: Legubicin - Shanghai Affinity Biopharmaceutical; QHL-108Latest Information Update: 25 Dec 2023
At a glance
- Originator Shanghai Affinity Biopharmaceutical
- Class Anthracyclines; Antineoplastics; Cytostatic antibiotics; Doxorubicins; Drug conjugates
- Mechanism of Action DNA intercalators; Type II DNA topoisomerase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase II/III Soft tissue sarcoma
- Phase II Adenocarcinoma
- Preclinical Solid tumours
Most Recent Events
- 22 Dec 2023 QHL 108 is available for licensing as of 22 Dec 2023. http://www.affinitybiopharma.com/en/cooperation.html (Shanghai Affinity Biopharmaceutical website, December 2023)
- 22 Dec 2023 Phase-II clinical trials in Adenocarcinoma (Parenteral), before December 2023 (Shanghai Affinity Biopharmaceutical pipeline, December 2023)
- 22 Dec 2023 Preclinical trials in Solid tumours in China (Parenteral), before December 2023 (Shanghai Affinity Biopharmaceutical pipeline, December 2023)