Drug Profile

ETX 19477

Alternative Names: ETX-19477

Latest Information Update: 29 Jul 2026

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At a glance

Originator 858 Therapeutics
Class Antineoplastics; Small molecules
Mechanism of Action Poly ADP ribose glycohydrolase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Highest Development Phases

Phase I/II Solid tumours

Most Recent Events

02 Jun 2026 Updated efficacy, adverse events and pharmacodynamics data from a phase I/II ERADIC8 trial in Solid tumours presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)
21 May 2026 Adverse events and efficacy data from a phase I/II trial in Solid tumours released by 858 Therapeutics
08 Jan 2026 Pharmacodynamics data from a preclinical trial in Cancer released by 858 Therapeutics

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