Drug Profile

ETX 19477

Alternative Names: ETX-19477

Latest Information Update: 02 Feb 2026

Price :

$50 ^*

Note:

Adis is an information provider. We do not sell or distribute actual drugs.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

Originator 858 Therapeutics
Class Antineoplastics; Small molecules
Mechanism of Action Poly ADP ribose glycohydrolase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Highest Development Phases

Phase I/II Solid tumours

Most Recent Events

08 Jan 2026 Pharmacodynamics data from a preclinical trial in Cancer released by 858 Therapeutics
08 Jan 2026 ETX 19477 receives Fast Track designation for Ovarian cancer (Second-line therapy or greater, In adults) in USA
13 May 2024 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Recurrent, Inoperable/Unresectable) in USA (PO) (NCT06395519)

You need to be a logged in or subscribed to view this content

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial (opens in a new window)

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com