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ETX 19477

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Drug Profile

ETX 19477

Alternative Names: ETX-19477

Latest Information Update: 17 May 2024

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At a glance

  • Originator 858 Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Poly ADP ribose glycohydrolase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 02 May 2024 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Recurrent, Inoperable/Unresectable, Monotherapy) in USA (PO) (NCT06395519)
  • 05 Apr 2024 Pharmacokinetics and pharmacodynamics data from a preclinical trial in Solid tumour presented at the115th Annual Meeting of the American Association for Cancer Research (AACR-2024)
  • 20 Dec 2023 858 Therapeutics plans a phase I trial in Solid tumours (Late-stage disease) in US in 1H of 2024

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