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LW 231

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Drug Profile

LW 231

Alternative Names: LW-231

Latest Information Update: 21 Oct 2025

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At a glance

  • Originator Longwood Biopharma
  • Class Antivirals; Small molecules
  • Mechanism of Action CGAS protein modulators; Nucleocapsid protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Hepatitis B

Most Recent Events

  • 02 Oct 2025 Phase-I/II clinical trials in Hepatitis B (Treatment-naive) in China (PO) (NCT07179575)
  • 18 Sep 2025 Longwood Biopharma plans a phase I/II trial for Hepatitis B (Treatment-naive) in China (PO, Tablet) (NCT07179575)
  • 04 Jan 2024 LW 231 is available for licensing as of 04 Jan 2024. https://www.lwbpsh.com/en/research (Longwood Biopharma website, January 2024)

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