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VS 041

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Drug Profile

VS 041

Alternative Names: VS-041

Latest Information Update: 28 Nov 2025

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At a glance

  • Originator Vasa Therapeutics
  • Class Antifibrotics; Heart failure therapies; Small molecules
  • Mechanism of Action Matrix metalloproteinase 2 inhibitors; Matrix metalloproteinase 9 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Heart failure

Most Recent Events

  • 18 Nov 2025 VS 041 receives Fast Track designation for Heart failure [PO,Tablet,BID] (Treatment-experienced) in USA
  • 04 Nov 2025 Phase-I clinical trials in Heart failure (Treatment-experienced) in USA (PO) (NCT07219511)
  • 16 Oct 2025 Vasa Therapeutics plans to initiate a phase Ic trial for Heart Failure in the US

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