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ZPC 21

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Drug Profile

ZPC 21

Alternative Names: IM-1021; ZPC-21

Latest Information Update: 18 Mar 2025

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At a glance

  • Originator Zentalis Pharmaceuticals
  • Developer Immunome
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I B-cell lymphoma; Solid tumours

Most Recent Events

  • 26 Feb 2025 Phase-I clinical trials in B-cell lymphoma (Late-stage disease, Second-line therapy or greater) in USA (IV) (NCT06823167)
  • 26 Feb 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater) in USA (IV) (NCT06823167)
  • 13 Jan 2025 US FDA approves IND application for ZPC 21 in Cancer

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