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KT 621

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Drug Profile

KT 621

Alternative Names: KT-621

Latest Information Update: 11 Nov 2025

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At a glance

  • Originator Kymera Therapeutics
  • Class Anti-infectives; Anti-inflammatories; Antiasthmatics; Skin disorder therapies; Small molecules
  • Mechanism of Action STAT6 transcription factor degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Atopic dermatitis
  • Phase I Immunological disorders
  • Preclinical Asthma

Most Recent Events

  • 04 Nov 2025 Kymera Therapeutics completes enrollment in a phase-Ib BroADen trial in Atopic dermatitis in USA (PO) before November 2025 (NCT06945458)
  • 04 Nov 2025 Kymera Therapeutics plans a phase III registration studies across multiple Type 2 dermatology, gastroenterology and respiratory indications
  • 15 Oct 2025 Phase-II clinical trials in Atopic dermatitis in USA (PO) before October 2025 (NCT07217015)

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