Drug Profile

KT 621

Alternative Names: KT-621

Latest Information Update: 28 Sep 2026

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At a glance

Originator Kymera Therapeutics
Class Anti-infectives; Anti-inflammatories; Antiasthmatics; Skin disorder therapies; Small molecules
Mechanism of Action STAT6 transcription factor degraders

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Highest Development Phases

Phase II Asthma; Atopic dermatitis
Phase I Immunological disorders

Most Recent Events

16 Sep 2026 Kymera Therapeutics initiates the phase I trial (In volunteers) in USA (NCT07823205).
05 Aug 2026 Kymera Therapeutics initiated a phase I trial in healthy volunteers in Japan (PO)
30 Jun 2026 Kymera Therapeutics initiates enrollment in a phase-II BREADTH-EXT trial in Asthma in USA (PO) (NCT07677059)

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