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KT 621

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Drug Profile

KT 621

Alternative Names: KT-621

Latest Information Update: 25 May 2026

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At a glance

  • Originator Kymera Therapeutics
  • Class Anti-infectives; Anti-inflammatories; Antiasthmatics; Skin disorder therapies; Small molecules
  • Mechanism of Action STAT6 transcription factor degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Asthma; Atopic dermatitis
  • Phase I Immunological disorders

Most Recent Events

  • 15 May 2026 Efficacy, adverse events and pharmacodynamics data from the phase Ib BroADen trial in Atopic dermatitis released by Kymera Therapeutics
  • 13 Apr 2026 KT 621 receives Fast Track designation for Asthma [PO,once-daily] in USA
  • 28 Mar 2026 Efficacy, adverse events and pharmacodynamics data from the phase Ib BroADen trial in Atopic dermatitis released by Kymera Therapeutics

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