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OP 3136

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Drug Profile

OP 3136

Alternative Names: OP-3136

Latest Information Update: 06 May 2025

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At a glance

  • Originator Olema Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action KAT6A protein inhibitors; KAT6B protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I HER2 positive breast cancer; Non-small cell lung cancer; Prostate cancer
  • Preclinical Ovarian cancer

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from preclinical trial in Non-small cell lung cancer, Prostate cancer and Ovarian cancer released by Olema Pharmaceuticals
  • 25 Mar 2025 Preclinical trials in Ovarian cancer in USA (PO)
  • 16 Dec 2024 Phase-I clinical trials in HER2-positive-breast-cancer (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) (NCT06784193)

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