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KTX 049

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Drug Profile

KTX 049

Alternative Names: KTX-049

Latest Information Update: 21 Feb 2024

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At a glance

  • Originator Kymera Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto-oncogene protein c-mdm2 degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Merkel cell carcinoma

Most Recent Events

  • 11 Oct 2023 Preclinical trials in Merkel cell carcinoma in USA (unspecified route), prior to October 2023
  • 11 Oct 2023 Pharmacodynamics data from a preclinical trial in Merkel cell carcinoma presented at the International Conference on Molecular Targets and Cancer Therapeutics 2023 (AACR-NCI-EORTC-2023)
  • 21 Oct 2018 Kymera Therapeutics files for patent protection for protein degraders worldwide

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