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XL 495

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Drug Profile

XL 495

Alternative Names: XL-495

Latest Information Update: 14 Oct 2024

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At a glance

  • Originator Exelixis
  • Class Antineoplastics; Small molecules
  • Mechanism of Action PKMYT1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 08 Oct 2024 Phase-I clinical trials in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) (NCT06630247)
  • 08 Oct 2024 Phase-I clinical trials in Solid tumours (Monotherapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) (NCT06630247)
  • 07 Jan 2024 Exelixis plans to file an Investigational New Drug (IND) application in Solid tumours in the second half of 2024

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