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CPL 976 MMAE

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Drug Profile

CPL 976 MMAE

Alternative Names: CPL-976-MMAE; CPL976 H-MMAE

Latest Information Update: 17 Jul 2026

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At a glance

  • Originator Celon Pharma
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action Apoptosis stimulants; Axl receptor tyrosine kinase inhibitors; B7-H1 antigen inhibitors; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 22 Apr 2026 Pharmacokinetics and pharmacodynamics data from a preclinical studies in Solid tumours presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR-2026)
  • 11 Oct 2023 Preclinical trials in Solid tumours in Poland (Parenteral)
  • 11 Oct 2023 Pharmacodynamics data from a preclinical trial in Solid tumours presented at the International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC-2023)

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