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Talicabtagene autoleucel - ImmunoACT

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Drug Profile

Talicabtagene autoleucel - ImmunoACT

Alternative Names: Actaly-cel; Actalycabtagene autoleucel - ImmunoACT; HCAR-19; NexCAR19; tali-cel

Latest Information Update: 25 Jul 2025

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At a glance

  • Originator ImmunoACT
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Marketed B-cell lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 04 Apr 2024 Launched for B-cell lymphoma (Second-line therapy or greater) in India (IV) (ImmunoACT pipeline, July 2025)
  • 04 Apr 2024 Launched for Precursor B-cell lymphoblastic leukaemia-lymphoma (Second-line therapy or greater) in India (IV) (ImmunoACT pipeline, July 2025)
  • 27 Mar 2024 Talicabtagene autoleucel is available for licensing as of 29 Jan 2024. https://www.immunoact.com/products (ImmunoACT pipeline, March 2024)

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