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AOP 208

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Drug Profile

AOP 208

Alternative Names: AOP-208; LB-208

Latest Information Update: 04 May 2026

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At a glance

  • Originator Leukos Biotech
  • Developer AOP Orphan Pharmaceuticals AG; Leukos Biotech
  • Class Antineoplastics
  • Mechanism of Action Serotonin 1B receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Lymphoma; Solid tumours
  • Preclinical Acute myeloid leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 15 Apr 2026 Aop Orphan Pharmaceuticals plans a phase I/II trial in Acute myeloid leukemia and Myelodysplastic syndrome (Second-line therapy or greater) in Spain (PO) in May 2026 (CTIS2025-523396-38-00)
  • 01 Oct 2024 AOP Orphan Pharmaceuticals in-licenses AOP 208 from Leukos Biotech
  • 01 Oct 2024 Phase-I clinical trials in Lymphoma, Solid tumours (PO)

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