TRX 103
Alternative Names: TRX-103Latest Information Update: 07 Feb 2025
At a glance
- Originator Tr1X
- Class Anti-inflammatories; Gene therapies; Regulatory T lymphocyte cell therapies
- Mechanism of Action Interleukin-10 expression stimulants; Regulatory T-lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II Crohn's disease; Graft-versus-host disease
- Preclinical Inflammatory bowel diseases
Most Recent Events
- 01 Feb 2025 Phase-I/II clinical trials in Crohn's disease (Treatment-experienced) in USA (Parenteral) (NCT06721962)
- 07 Aug 2024 Tr1X plans a phase I/IIa trial in Crohn’s disease (Treatment-experienced) in USA (Parenteral) in December 2024 (NCT06721962)
- 10 Jul 2024 Tr1X plans to submit IND application to the USA FDA for Crohn's disease (Treatment experienced) (Parenteral), in the second half of 2024