YZJ 5053
Alternative Names: SHY-1901; YZJ-5053Latest Information Update: 16 Jul 2026
At a glance
- Originator Shanghai Haiyan Pharmaceutical Technology
- Class Antineoplastics; Small molecules
- Mechanism of Action Adenosine A2A receptor antagonists; Adenosine A2B receptor antagonists
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Solid tumours
Most Recent Events
- 09 Jul 2025 Shanghai Haiyan Pharmaceutical Technology completes a phase-I trial in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO) (NCT06209385)
- 08 Feb 2024 Shanghai Haiyan Pharmaceutical receives an IND approval of YZJ 5053 for the treatment of solid tumours in China, prior to February 2024
- 11 Aug 2023 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO) (NCT06209385)