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ONC 841

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Drug Profile

ONC 841

Alternative Names: Anti-SIGLEC10 antibody - OncoC4; ONC-841

Latest Information Update: 06 Sep 2024

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At a glance

  • Originator OncoImmune
  • Developer OncoC4
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; SIGLEC10 protein inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 04 Sep 2024 Phase-I clinical trials in Solid tumours (Metastatic disease, Late-stage disease) in USA (IV) (NCT06352359)
  • 23 Apr 2024 US FDA approves IND application for ONC 841 in Solid tumours in USA
  • 23 Apr 2024 Pharmacodynamics data from preclinical trial in Solid tumours released by OncoC4

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