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KME 0584

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Drug Profile

KME 0584

Alternative Names: KME-0584

Latest Information Update: 29 Feb 2024

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At a glance

  • Originator Cincinnati Children's Hospital Medical Center; National Center for Advancing Translational Sciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Interleukin-1 receptor-associated kinase inhibitors; IRAK4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia; Myelodysplastic syndromes; Unspecified

Most Recent Events

  • 16 Feb 2024 US FDA approves IND application for KME 0584 in Acute myeloid leukemia and Myelodysplastic syndromes
  • 31 Jan 2024 KME 0584 is available for licensing as of 31 Jan 2024. https://www.kurometherapeutics.com/partnering/ (Kurome Therapeutics website, January 2024)
  • 31 Jan 2024 Preclinical trials in Unspecified in USA (unspecified route) before January 2024 (Kurome Therapeutics pipeline, January 2024)

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