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Mocertatug rezetecan - GSK

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Drug Profile

Mocertatug rezetecan - GSK

Alternative Names: GSK-5733584

Latest Information Update: 22 Dec 2025

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At a glance

  • Originator GSK
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action Undefined mechanism
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 16 Dec 2025 GlaxoSmithKline plans phase-III BEHOLD-Endometrial01 trial for Endometrial cancer (Recurrent, Second-line therapy or greater, Metastatic disease) in March 2026 (Parenteral) (NCT07286331)
  • 16 Dec 2025 GlaxoSmithKline plans phase-III BEHOLD-Ovarian01 trial for Ovarian cancer, Peritoneal cancer, Fallopian-tube cancer (Late-stage disease, Second-line therapy or greater) in March 2026 (Parenteral) (NCT07286266)
  • 04 Apr 2025 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Combination therapy, Second-line therapy or greater) in Japan (IV) (NCT06796907)

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