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FXS 7553

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Drug Profile

FXS 7553

Alternative Names: EXPD-101; FXS-7553; XH-S004

Latest Information Update: 21 Aug 2026

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At a glance

  • Originator S-Infinity Pharmaceuticals
  • Developer Expedition Therapeutics; S-Infinity Pharmaceuticals
  • Class Antibronchitics; Small molecules
  • Mechanism of Action Cathepsin C inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Bronchiectasis; Chronic obstructive pulmonary disease

Most Recent Events

  • 13 Aug 2026 Phase-II clinical trials in Chronic obstructive pulmonary disease in China (PO)
  • 05 Aug 2026 Pharmacokinetics and adverse events data from a phase-I trial in Bronchiectasis (In volunteers) released by Expedition Therapeutics
  • 14 Jul 2026 Phase-II clinical trials in Bronchiectasis in China (PO) (Shanghai Fosun Pharmaceutical pipeline, July 2026) (NCT06981091)

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