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AEX 2

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Drug Profile

AEX 2

Alternative Names: AEX-2

Latest Information Update: 22 Mar 2024

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At a glance

  • Originator Aexon Labs
  • Developer Aexon Labs; NLS Pharmaceutics Ltd
  • Class Sleep disorder therapies
  • Mechanism of Action Orexin receptor type 1 agonists; Orexin receptor type 2 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Narcolepsy; Neurodegenerative disorders

Most Recent Events

  • 20 Mar 2024 AEX 2 licensed to NLS Pharmaceutics worldwide
  • 20 Mar 2024 Aexon Labs plans a phase-I first-in-human and phase-Ib proof-of-concept (POC) studies, in early 2025
  • 01 Dec 2023 NLS Pharmaceutics enters into an option agreement with Aexon Labs to develop and commercialize Dual Orexin Receptor Agonists for Narcolepsy and Neurodegenerative disorders (9409268; 9406850)

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