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TYK 00540

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Drug Profile

TYK 00540

Alternative Names: TYK-00540

Latest Information Update: 27 Mar 2026

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At a glance

  • Originator TYK Medicine
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 2 inhibitors; Cyclin-dependent kinase 4 inhibitors; Cyclin-dependent kinase 6 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 17 Oct 2025 Efficacy, pharmacokinetics and adverse events data from a phase I trial in Solid tumours presented at the 50th European Society for Medical Oncology Congress (ESMO-2025)
  • 05 Aug 2025 TYK Medicines plans a phase-I/II trial for Prostate cancer (Hormone refractory, Metastatic disease, Second-line therapy or greater, Combination therapy) in China (PO), (NCT07104643)
  • 02 Jan 2024 Phase-I/II clinical trials in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO) (NCT06950086)

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