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MGC 026

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Drug Profile

MGC 026

Alternative Names: MGC-026

Latest Information Update: 26 Dec 2025

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At a glance

  • Originator MacroGenics
  • Class Alkaloids; Antibodies; Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 22 Oct 2025 Pharmacodynamics data from a preclinical trial in Castration-resistant prostate cancer presented at the International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)
  • 09 May 2024 Pharmacodynamics data from a preclinical trial in Solid tumour released by MacroGenics
  • 05 Apr 2024 Adverse events, pharmacodynamics and pharmacokinetics data from a preclinical studies in Solid tumour wre presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)

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