Drug Profile

Nomelcitinib - InventisBio

Alternative Names: D-2570

Latest Information Update: 30 Jul 2026

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At a glance

Originator InventisBio
Class Amides; Amines; Anti-inflammatories; Antipsoriatics; Antirheumatics; Cyclopropanes; Organic deuterium compounds; Pyridazines; Pyridines; Small molecules; Sulfones
Mechanism of Action TYK2 kinase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase III Plaque psoriasis
Phase II Psoriatic arthritis; Systemic lupus erythematosus; Ulcerative colitis; Vitiligo

Most Recent Events

14 Jul 2026 InventisBio initiates phase I pharmacokinetics trial (In volunteers) in China (PO, Tablet) (NCT07715149)
01 Jul 2026 Chemical structure information added
11 Jun 2026 Phase-II clinical trials in Vitiligo in China (PO) (NCT07625891)

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