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Nintedanib dry powder inhaler - MannKind Corporation

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Drug Profile

Nintedanib dry powder inhaler - MannKind Corporation

Alternative Names: MNKD-201; nintedanib DPI - MannKind Corporation

Latest Information Update: 13 Nov 2024

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At a glance

  • Originator MannKind Corporation
  • Class Acetamides; Antifibrotics; Antineoplastics; Esters; Indoles; Piperazines; Skin disorder therapies; Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Lymphocyte specific protein tyrosine kinase p56(lck) inhibitors; Lyn protein-tyrosine kinase inhibitors; Platelet-derived growth factor alpha receptor antagonists; Platelet-derived growth factor beta receptor antagonists; Src-family kinase inhibitors; Type 1 fibroblast growth factor receptor antagonists; Type 3 fibroblast growth factor receptor antagonists; Type-2 fibroblast growth factor receptor antagonists; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists; Vascular endothelial growth factor receptor-3 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Idiopathic pulmonary fibrosis

Most Recent Events

  • 07 Nov 2024 MannKind Corporation plans to have a End-of-Phase-I meeting with US FDA to advance Nintedanib dry powder inhaler into the next phase of development in the first half of 2025
  • 04 Nov 2024 Mannkind Corporation completes a phase I trial in Idiopathic pulmonary fibrosis (In volunteers) in USA (Inhalation) (NCT06532942)
  • 28 May 2024 Phase-I clinical trials in Idiopathic pulmonary fibrosis (In volunteers) in USA (Inhalation) (NCT06532942)

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