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LY 3954068

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Drug Profile

LY 3954068

Alternative Names: LY-3954068; MAPT siRNA

Latest Information Update: 19 Feb 2025

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At a glance

  • Originator Eli Lilly and Company
  • Class Antidementias; Small interfering RNA
  • Mechanism of Action RNA interference; Tau protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Alzheimer's disease

Most Recent Events

  • 15 Aug 2024 Phase-I clinical trials in Alzheimer's disease (In adults, In the elderly) in Japan (Intrathecal) (NCT06297590)
  • 07 Mar 2024 Eli Lilly and Company plans a phase I trial for Alzheimer Disease (In adults, In elderly) in USA, Japan and United Kingdom (NCT06297590)
  • 07 Mar 2024 Preclinical trials in Alzheimer's disease in USA (Intrathecal)

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