Drug Profile

Latrepirdine - Bigespas

Alternative Names: Dimebon; DMB-I

Latest Information Update: 03 Dec 2025

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At a glance

Originator BIGESPAS
Class Antidementias; Behavioural disorder therapies; Indoles; Small molecules
Mechanism of Action Acetylcholinesterase inhibitors; Butyrylcholinesterase inhibitors; NMDA receptor antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

11 Sep 2025 Phase-III clinical trials in Dementia (In the elderly, In adults) in Russia (PO) (NCT07251023)
31 Jan 2025 Bigespas completes a phase-II/III clinical trials in Dementia (In adults, In the elderly) in Russia (PO) (NCT06292351)
27 Dec 2023 Phase-II/III clinical trials in Dementia (In adults, In the elderly) in Russia (PO) (NCT06292351)

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