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MRT 8102

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Drug Profile

MRT 8102

Alternative Names: MRT-8102

Latest Information Update: 17 Nov 2025

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At a glance

  • Originator Monte Rosa Therapeutics
  • Class Anti-inflammatories; Small molecules
  • Mechanism of Action NEK7 protein degraders; NLRP3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Inflammation

Most Recent Events

  • 08 Nov 2025 Pharmacodynamics data from a preclinical trials in Inflammation released by Monte Rosa Therapeutics
  • 27 Jun 2025 Phase-I clinical trials in Inflammation (PO) (NCT07119125)
  • 11 Jun 2025 Pharmacodynamics data from a preclinical study in inflammation presented at the 26th Annual Congress of the European League Against Rheumatism (EULAR-2025)

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