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MGC 028

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Drug Profile

MGC 028

Alternative Names: MGC-028

Latest Information Update: 02 Apr 2025

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At a glance

  • Originator MacroGenics
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 19 Mar 2025 Phase-I clinical trials in Solid tumours (Metastatic disease, Late-stage disease, Second-line therapy or greater, Inoperable/Unresectable) in USA (IV) (NCT06723236),
  • 09 Dec 2024 MacroGenics plans to initiates a phase I trial for Solid tumours (Late-stage disease, Metastatic disease, Inoperable/unresectable, Second-line therapy or greater) in unknown location (IV) (NCT06723236)
  • 05 Nov 2024 MacroGenics submits an IND application to the US FDA for Solid tumours in October 2024

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