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MET 097i

Drug Profile

MET 097i

Alternative Names: GLP-1 receptor agonist - Pfizer; MET-097; MET-097o; MET-097i; PF-08653944

Latest Information Update: 18 Feb 2026

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At a glance

  • Originator Metsera
  • Developer Pfizer
  • Class Antihyperglycaemics; Glucagon-like peptides; Obesity therapies; Peptides
  • Mechanism of Action Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Obesity
  • Phase II Type 2 diabetes mellitus

Most Recent Events

  • 12 Feb 2026 Pfizer plans a phase III VESPER-5 trial for Obesity and Type 2 diabetes mellitus (SC, Injection) (CTIS2025-523975-48-00) (NCT07400653)
  • 04 Feb 2026 Pfizer initiates enrolment in a phase I relative bioavailability trial for Obesity in USA (SC, Injection) (NCT07400679)
  • 04 Feb 2026 Pfizer plans a phase I relative bioavailability trial for Obesity (SC, Injection)(NCT07400679)

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