Drug Profile

MET 097

Alternative Names: GLP-1 receptor agonist - Metsera; MET-097; MET-097_o; MET-097i

Latest Information Update: 06 Oct 2025

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At a glance

Originator Metsera
Class Antihyperglycaemics; Glucagon-like peptides; Obesity therapies; Peptides
Mechanism of Action Glucagon-like peptide-1 receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Obesity; Type 2 diabetes mellitus
Phase I/II Metabolic disorders

Most Recent Events

29 Sep 2025 Adverse events data from the phase IIb VESPER-3 trial in Obesity released by Metsera
29 Sep 2025 Updated efficacy and adverse events data from the phase IIb VESPER-1 trial in Obesity released by Metsera
31 Jul 2025 Metsera intends to pursue regulatory approval in USA, pursuant to a BLA (Metsera pipeline, July 2025)

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